ER-27319, an acridone derivative, is a potent and selective SYK inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 µM and can be used for study in allergic diseases[1][2].
Molekulargewicht:
370.40
Reinheit:
98.66
CAS Nummer:
[201010-95-9]
Formel:
C20H22N2O5
Target-Kategorie:
Syk
Anwendungsbeschreibung:
MCE Product type: Reference compound
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