Gamcemetinib (CC-99677) is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM). Gamcemetinib is extracted from patent WO2020236636, compound 1[1].
Molekulargewicht:
469.94
Reinheit:
99.06
CAS Nummer:
[1887069-10-4]
Formel:
C22H20ClN5O3S
Target-Kategorie:
MAPKAPK2 (MK2)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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