Azetukalner (XEN1101) is a selective and orally active Kv7.2/Kv7.3 potassium channel opener with an EC50 of 27 nM. Azetukalner is approximately 4-fold more selective for Kv7.2/7.3 over Kv7.3/7.5 (EC50 of 94 nM) and Kv7.4 (EC50 of 113 nM) channels. Azetukalner exhibits a selectivity >100-fold for Kv7 channels over other ion channels and receptors. Azetukalner can be used for the study of focal epilepsy[1][2].
Molekulargewicht:
368.49
Reinheit:
99.61
CAS Nummer:
[1009344-33-5]
Formel:
C23H29FN2O
Target-Kategorie:
Potassium Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound
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