Oritinib, CAS [[2035089-28-0]]
Artikelnummer:
MCE-HY-139920
| Artikelname: |
Oritinib, CAS [[2035089-28-0]] |
| Artikelnummer: |
MCE-HY-139920 |
| Hersteller Artikelnummer: |
HY-139920 |
| Alternativnummer: |
MCE-HY-139920-100MG,MCE-HY-139920-10MMX1ML,MCE-HY-139920-5MG,MCE-HY-139920-10MG,MCE-HY-139920-50MG,MCE-HY-139920-25MG |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| Alternative Synonym: |
SH-1028 |
| Oritinib (SH-1028), an irreversible third-generation EGFR TKI, overcomes T790M-mediated resistance in non-small cell lung cancer. Oritinib (SH-1028), a mutant-selective inhibitor of EGFR kinase activity, inhibits EGFRWT, EGFRL858R, EGFRL861Q, EGFRL858R/T790M, EGFRd746-750 and EGFRd746-750/T790M kinases, with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM, respectively[1]. |
| Molekulargewicht: |
539.67 |
| Reinheit: |
99.59 |
| CAS Nummer: |
[2035089-28-0] |
| Formel: |
C31H37N7O2 |
| Target-Kategorie: |
EGFR |
| Anwendungsbeschreibung: |
Reference compound |
