Prucalopride (hydrochloride), CAS [[179474-80-7]] Preis auf Anfrage
Artikelnummer:
MCE-HY-14152
Hersteller Artikelnummer:
HY-14152
Alternativnummer:
MCE-HY-14152-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Prucalopride hydrochloride is an orally active, selective and specific 5-HT4 receptor agonist (high affinity), with pKis of 8.6 and 8.1 for human 5-HT4a/4b receptors, respectively. Prucalopride hydrochloride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride hydrochloride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride hydrochloride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer[1][2][3].
Molekulargewicht:
404.33
CAS Nummer:
[179474-80-7]
Formel:
C18H27Cl2N3O3
Target-Kategorie:
5-HT Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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