(1R,3S)-Compound E is the isomer of Compound E (HY-14176), and can be used as an experimental control. Compound E is a gamma-secretase inhibitor. Compound E bloks beta-amyloid(40), beta-amyloid(42), and Notch gamma-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
Molekulargewicht:
490.50
Reinheit:
99.82
CAS Nummer:
[504428-17-5]
Formel:
C27H24F2N4O3
Target-Kategorie:
gamma-secretase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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