MS4322 (isomer), CAS [[2601727-80-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: MS4322 (isomer), CAS [[2601727-80-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-141877B
• Hersteller Artikelnummer: HY-141877B
• Alternativnummer: MCE-HY-141877B-1MG,MCE-HY-141877B-50MG,MCE-HY-141877B-25MG,MCE-HY-141877B-10MG,MCE-HY-141877B-5MG,MCE-HY-141877B-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: YS43-22 (isomer)

Produktbeschreibung

MS4322 (YS43-22) isomer is an isomer of MS4322. MS4322 is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC50 of 1.1 µM in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC50 of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5. MS4322 can be used for the research of breast cancer, lung cancer, and hepatocellular cancer. (Pink: PRMT5 ligand (HY-173092), Blue: E3 ligase ligand HY-112078), Black: linker (HY-124780), E3+linker (HY-173093 ))[1].

Produkteigenschaften

• Molekulargewicht: 1101.32
• Reinheit: 99.87
• CAS Nummer: [2601727-80-2]
• Formel: C55H76N10O12S
• Target-Kategorie: Histone Methyltransferase,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound