Siramesine (hydrochloride), CAS [[224177-60-0]]

Produktübersicht

• Artikelname: Siramesine (hydrochloride), CAS [[224177-60-0]]
• Artikelnummer: MCE-HY-14221A
• Hersteller Artikelnummer: HY-14221A
• Alternativnummer: MCE-HY-14221A-2MG,MCE-HY-14221A-10MG,MCE-HY-14221A-10MMX1ML,MCE-HY-14221A-100MG,MCE-HY-14221A-5MG,MCE-HY-14221A-25MG,MCE-HY-14221A-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: Lu 28-179 (hydrochloride)

Produktbeschreibung

Siramesine (Lu 28-179) hydrochloride is a potent sigma-2 receptor agonist. Siramesine hydrochloride has a subnanomolar affinity for sigma-2 receptors (IC50=0.12 nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC50=17 nM). Siramesine hydrochloride triggers cell death through destabilisation of mitochondria, but not lysosomes. Anti-cancer activity[1][2][3].

Produkteigenschaften

• Molekulargewicht: 491.04
• Reinheit: 99.69
• CAS Nummer: [224177-60-0]
• Formel: C30H32ClFN2O
• Target-Kategorie: Ferroptosis,Sigma Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound