Carboxylesterase-IN-3 (compound 4y) is a potent inhibitor of Carboxylesterase Notum with an IC50 less than or equal to 10 nM. Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity. Carboxylesterase-IN-3 has the potential for the research of cancer disease[1].
Molekulargewicht:
313.16
Reinheit:
98.27
CAS Nummer:
[2764748-92-5]
Formel:
C11H6Cl2N4OS
Target-Kategorie:
Carboxylesterase (CES),Wnt
Anwendungsbeschreibung:
MCE Product type: Reference compound
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