GSK-3beta inhibitor 7 is a GSK-3beta inhibitor with an IC50 value of 5.25 µM. GSK-3beta inhibitor 7 is inserted into the ATP-binding binding pocket of GSK-3beta and forms hydrogen-bond. GSK-3beta inhibitor 7 shows high hepatocyte glucose uptake (83.5%), and can be used in the research of numerous diseases like diabetes, inflammation, cancer, Alzheimers disease, and bipolar disorder[1].
Molekulargewicht:
547.47
Formel:
C27H23BrN4O2S
Target-Kategorie:
GSK-3
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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