PF15 (TFA)

Produktübersicht

• Artikelname: PF15 (TFA)
• Artikelnummer: MCE-HY-143286A
• Hersteller Artikelnummer: HY-143286A
• Alternativnummer: MCE-HY-143286A-50MG,MCE-HY-143286A-5MG,MCE-HY-143286A-10MG,MCE-HY-143286A-25MG,MCE-HY-143286A-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PF15 TFA is a PROTAC connected by ligands for FLT3 kinase and CRBN. PF15 TFA is a high selective FLT3-ITD degrader,with a DC50 of 76.7 nM. PF15 TFA significantly inhibits the proliferation of FLT3-ITD-positive cells,can down-regulate the phosphorylation of FLT3 and STAT5. PF15 TFA also inhibits tumor growth in mouse models and can be used in study of leukemia[1].

Produkteigenschaften

• Molekulargewicht: 969.97
• Reinheit: 99.72
• Formel: C46H50F3N13O8
• Target-Kategorie: FLT3,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound