ULK1-IN-2 (compound 3s) is a potent ULK1 inhibitor. ULK1-IN-2 shows highest cytotoxic effect against cancer cell lines, with IC50 of 1.94 µM in A549. ULK1-IN-2 can induce apoptosis and simultaneously block autophagy, and can be used to study NSCLC (Non-small cell lung cancer)[1].
Molekulargewicht:
495.26
Reinheit:
98.34
CAS Nummer:
[2497409-01-3]
Formel:
C19H16BrFN4O6
Target-Kategorie:
AMPK,Apoptosis,Autophagy,FAK,ULK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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