AC-55541 is a highly selective protease-activated receptor 2 (PAR2) agonist (pEC50=6.7), displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. AC-55541 has pEC50 values of 5.9 and 6.6 in PI hydrolysis assays and Ca2+ mobilization assays and exhibits pronociceptive activity in vivo[1].
Molekulargewicht:
518.36
Reinheit:
99.40
CAS Nummer:
[916170-19-9]
Formel:
C25H20BrN5O3
Target-Kategorie:
Protease Activated Receptor (PAR)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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