GSK-9772 is a Liver X Receptor (LXR) modulator of the N-phenyl tertiary amine class (NPTAs) with high affinity for LXR beta ligand (IC50=30 nM). GSK-9772 has anti-inflammatory activity by binding to LXR, specifically by interacting with the region associated with the transcriptional repression function of the receptor, thereby inhibiting the expression of pro-inflammatory genes. GSK-9772 can be used in the study of inflammatory and neurodegenerative diseases[1].
Molekulargewicht:
490.27
CAS Nummer:
[928035-84-1]
Formel:
C20H19Cl2F6NO2
Target-Kategorie:
LXR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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