Allolithocholic acid, CAS [[2276-94-0]]

Produktübersicht

• Artikelname: Allolithocholic acid, CAS [[2276-94-0]]
• Artikelnummer: MCE-HY-143712
• Hersteller Artikelnummer: HY-143712
• Alternativnummer: MCE-HY-143712-10MMX1ML,MCE-HY-143712-5MG,MCE-HY-143712-10MG,MCE-HY-143712-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Allolithocholic acid is an orally active metabolite of Lithocholic acid (HY-B0172). Allolithocholic acid is a dual GPBAR1 agonist (EC50 = 2.7 µM) and RORgammat inverse agonist (IC50 = 3.4 µM). Allolithocholic acid modulates immune and metabolic pathways, regulates immune cell polarization, prevents M1 macrophage and Th17 CD4 cell polarization. Allolithocholic acid improves insulin sensitivity, reduces liver lipid accumulation, reverses liver immunological, inflammatory and metabolic signaling dysregulation, restores bile acid homeostasis, adipose tissue histopathology/function, and intestinal microbiota composition, modulates intestinal immunity. Allolithocholic acid can be used for the researches of cancer, inflammayion, immunology and metabolic disease[1][2].

Produkteigenschaften

• Molekulargewicht: 376.57
• Reinheit: 99.69
• CAS Nummer: [2276-94-0]
• Formel: C24H40O3
• Target-Kategorie: Drug Metabolite,G protein-coupled Bile Acid Receptor 1,ROR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound