MK-1220 is a covalently reversible inhibitor of the hepatitis C virus (HCV) NS3/4A protease (NS3/4A protease) with a Ki of 0.02 nM. MK-1220 in cell models simulating viral replication exhibits EC50s of 4 (with 10% fetal bovine serum) and 11 nM (50% normal human serum). MK-1220 can be used for the study of chronic hepatitis C virus infection[1].
Molekulargewicht:
779.94
CAS Nummer:
[924270-31-5]
Formel:
C40H53N5O9S
Target-Kategorie:
HBV,HCV Protease
Anwendungsbeschreibung:
MCE Product type: Reference compound
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