Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of Substance P (HY-P0201). Casopitant mesylate is also a substrate and a weak-to-moderate inhibitor of CYP3A4. Casopitant mesylate can be used for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV)[1][2].
Molekulargewicht:
712.72
Reinheit:
99.83
CAS Nummer:
[414910-30-8]
Formel:
C31H39F7N4O5S
Target-Kategorie:
Cytochrome P450,Neurokinin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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