CYD19 is a potent Snail/HDAC dual target inhibitor. CYD19 displays potent inhibitory activity against HDAC1 with an IC50 of 0.405 µM and potent inhibition against Snail with a Kd of 0.18 µM. CYD19 increases histone H4 acetylation in HCT-116 cells and decreases the expression of Snail protein to induce cell apoptosis[1].
Molekulargewicht:
488.54
Reinheit:
99.76
CAS Nummer:
[2415281-52-4]
Formel:
C24H21FN8OS
Target-Kategorie:
HDAC
Anwendungsbeschreibung:
Reference compound
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