BSc5367 is a potent Nek1 inhibitor with an IC50 of 11.5 nM. NIMA-related protein kinase Nek1 is crucially involved in cell cycle regulation, DNA repair and microtubule regulation and dysfunctions of Nek1 play key roles in amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD) and several types of radiotherapy resistant cancer[1].
Molekulargewicht:
329.35
Reinheit:
98.21
CAS Nummer:
[3029584-84-4]
Formel:
C20H15N3O2
Target-Kategorie:
NEKs
Anwendungsbeschreibung:
Reference compound
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