NF-kappaB-IN-4 (compound 17) is a potent NF-kappaB pathway inhibitor with blood brain barrier (BBB) permeability. NF-kappaB-IN-4 exhibits potential anti-neuroinflammatory activity with low toxicity. NF-kappaB-IN-4 can block the activation and phosphorylation of IkappaBalpha, reduce expression of NLRP3, and thus inhibit NF-kappaB activation. NF-kappaB-IN-4 can be used for neuroinflammation related diseases research[1].
Molekulargewicht:
322.34
Reinheit:
98.51
CAS Nummer:
[3033258-60-2]
Formel:
C18H15FN4O
Target-Kategorie:
Apoptosis,NF-kappaB
Anwendungsbeschreibung:
MCE Product type: Reference compound
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