Tuspetinib, CAS [[2294874-49-8]]

Produktübersicht

• Artikelname: Tuspetinib, CAS [[2294874-49-8]]
• Artikelnummer: MCE-HY-145015
• Hersteller Artikelnummer: HY-145015
• Alternativnummer: MCE-HY-145015-10MMX1ML,MCE-HY-145015-5MG,MCE-HY-145015-10MG,MCE-HY-145015-100MG,MCE-HY-145015-50MG,MCE-HY-145015-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: HM43239

Produktbeschreibung

Tuspetinib (HM43239) is an orally active and selective FLT3 inhibitor with IC50s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. Tuspetinib inhibits the kinase activity of FLT3 as a reversible type I inhibitor and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. Tuspetinib inhibits the proliferation and induces the apoptosis of leukemic cells[1][2][3].

Produkteigenschaften

• Molekulargewicht: 501.07
• Reinheit: 99.85
• CAS Nummer: [2294874-49-8]
• Formel: C29H33ClN6
• Target-Kategorie: Apoptosis,FLT3

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound