Dynole 2-24 is an indole-based dynamin GTPase inhibitor (IC50=0.56 µM for dynamin I). Dynole 2-24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC50(CME)=1.9 µM). Dynole 2-24 also shows 4.4-fold selectivity for dynamin I. Dynole 2-24 is active in-cell inhibitor of clathrin-mediated endocytosis[1]. CME: Clathrin mediated endocytosis
Molekulargewicht:
371.60
Reinheit:
99.07
CAS Nummer:
[1416313-72-8]
Formel:
C24H41N3
Target-Kategorie:
Dynamin
Anwendungsbeschreibung:
MCE Product type: Reference compound
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