Lometrexol (disodium), CAS [[120408-07-3]]

Produktübersicht

• Artikelname: Lometrexol (disodium), CAS [[120408-07-3]]
• Artikelnummer: MCE-HY-14521A
• Hersteller Artikelnummer: HY-14521A
• Alternativnummer: MCE-HY-14521A-10MG,MCE-HY-14521A-1MG,MCE-HY-14521A-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: DDATHF (disodium)

Produktbeschreibung

Lometrexol (DDATHF) disodium, an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol disodium can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol disodium has anticancer activity. Lometrexol disodium also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor[1][2][3].

Produkteigenschaften

• Molekulargewicht: 487.42
• Reinheit: 98
• CAS Nummer: [120408-07-3]
• Formel: C21H23N5Na2O6
• Target-Kategorie: Antifolate,Apoptosis,Bcl-2 Family,Caspase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1