AU-15330 is a proteolysis-targeting chimera (PROTAC) degrader of the SWI/SNF ATPase subunits, SMARCA2 and SMARCA4. AU-15330 induces potent inhibition of tumour growth in xenograft models of prostate cancer and synergizes with the AR antagonist enzalutamide. AU-15330 induces disease remission in castration-resistant prostate cancer (CRPC) models without toxicity[1].
Molekulargewicht:
755.93
Reinheit:
99.89
CAS Nummer:
[2380274-50-8]
Formel:
C39H49N9O5S
Target-Kategorie:
PROTACs,SWI/SNF Complex
Anwendungsbeschreibung:
MCE Product type: Reference compound
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