Clozapine (hydrochloride), CAS [[54241-01-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-14539A
Hersteller Artikelnummer:
HY-14539A
Alternativnummer:
MCE-HY-14539A-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
HF 1854 (hydrochloride)
Clozapine hydrochloride (HF 1854 hydrochloride) is an antipsychotic used for the research of schizophrenia. Clozapine hydrochloride has high affinity for a number of neuroreceptors. Clozapine hydrochloride is a potent antagonist of dopamine D2 with a Ki of 75 nM. Clozapine hydrochloride inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with Kis of 9.5 nM and 4 nM, respectively[1][2][3]. Clozapine hydrochloride is also a potent and selective agonist at the muscarinic M4 receptor (EC50=11 nM)[4].