NU5455 is a potent, selective, and orally active inhibitor of DNA-PKcs. NU5455 administration increases both the efficacy and the toxicity of a parenterally administered topoisomerase inhibitor. NU5455 enhances the activity of Doxorubicin released locally in liver tumor xenografts without inducing any adverse effect[1].
Molekulargewicht:
595.71
CAS Nummer:
[1257235-99-6]
Formel:
C34H33N3O5S
Target-Kategorie:
DNA-PK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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