8-Azanebularine, a compound with hydrogen in place of the C6 amino group, inhibits the ADAR2 reaction at high concentrations (IC50=15 mM). 8-Azanebularine is incorporated into an RNA structure recognized by human ADAR2 results in high-affinity binding (KD=2 nM). 8-Azanebularine can be used for the research of ADAR-catalyzed RNA-editing reaction[1].
Molekulargewicht:
253.21
Reinheit:
99.33
CAS Nummer:
[38874-46-3]
Formel:
C9H11N5O4
Target-Kategorie:
Adenosine Deaminase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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