Cudetaxestat (BLD-0409, PAT-409) is an orally active and noncompetitive autotaxin (ATX) inhibitor. Cudetaxestat inhibits the activity of ATX, reduces the production of LPA, and thereby blocks the signal transduction of the ATX-LPA axis. Cudetaxestat can still maintain nanomolar-level biochemical efficacy even when the concentration of the LPC substrate increases. Cudetaxestat can be used for the study of various diseases related to LPA including fibrosis, tumor metastasis, inflammation and autoimmune diseases, etc[1][2].
Molekulargewicht:
482.33
Reinheit:
98.32
CAS Nummer:
[1782070-21-6]
Formel:
C21H15Cl2F2N3O2S
Target-Kategorie:
LPL Receptor,Phosphodiesterase (PDE)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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