Safusidenib, CAS [[1898206-17-1]]

Produktübersicht

• Artikelname: Safusidenib, CAS [[1898206-17-1]]
• Artikelnummer: MCE-HY-145594
• Hersteller Artikelnummer: HY-145594
• Alternativnummer: MCE-HY-145594-25MG,MCE-HY-145594-5MG,MCE-HY-145594-10MG,MCE-HY-145594-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: AB-291, DS-1001

Produktbeschreibung

Safusidenib (AB-291, DS-1001) is an orally bioavailable, selective mutant IDH1 inhibitor. Safusidenib strongly inhibits mutant IDH1 but not wild-type IDH1. Safusidenib impairs tumor activity in chondrosarcoma[1]. Safusidenib exhibits activity against IDH1R132H, and IDH1R132C with IC50s of 15, and 130 nM in assays without any preincubation, respectively[2].

Produkteigenschaften

• Molekulargewicht: 535.78
• Reinheit: 98.11
• CAS Nummer: [1898206-17-1]
• Formel: C25H18Cl3FN2O4
• Target-Kategorie: Isocitrate Dehydrogenase (IDH)

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound