PR-104A (SN 27858) is the alcohol metabolite of phosphate proagent PR-104. PR-104A is a hypoxia-selective DNA cross-linking agent/DNA-damaging agent and cytotoxin. Antitumor Activity[1]. PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase. PR-104A can be used for the research of relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL)[2].
Molekulargewicht:
499.29
Reinheit:
98.98
CAS Nummer:
[680199-06-8]
Formel:
C14H19BrN4O9S
Target-Kategorie:
DNA Alkylator/Crosslinker,Drug Metabolite
Anwendungsbeschreibung:
MCE Product type: Reference compound
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