JPS016, CAS [[2669785-77-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: JPS016, CAS [[2669785-77-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-145816
• Hersteller Artikelnummer: HY-145816
• Alternativnummer: MCE-HY-145816-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

JPS016 is a class I histone deacetylase (HDAC) PROTAC inhibitor. JPS016 recruits the VHL E3 ligase (Ligands for E3 Ligase) to mediate the ubiquitination and proteasomal degradation of HDAC1, HDAC2 and HDAC3. JPS016 reduces the viability of colon cancer cells and induces Apoptosis. JPS016 activates the PINK1/Parkin mitochondrial Autophagy pathway, enhances cardiomyocyte viability, alleviates mitochondrial damage, and reduces mitochondrial ROS production in cells. JPS016 is applicable to research related to colon cancer and sepsis cardiomyopathy[1][2].

Produkteigenschaften

• Molekulargewicht: 898.12
• CAS Nummer: [2669785-77-5]
• Formel: C48H63N7O8S
• Target-Kategorie: Apoptosis,Autophagy,HDAC,PINK1/Parkin,PROTACs,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound