(R)-alpha7 nAchR-JAK2-STAT3 agonist 1

Produktübersicht

• Artikelname: (R)-alpha7 nAchR-JAK2-STAT3 agonist 1
• Artikelnummer: MCE-HY-146066A
• Hersteller Artikelnummer: HY-146066A
• Alternativnummer: MCE-HY-146066A-50MG,MCE-HY-146066A-5MG,MCE-HY-146066A-25MG,MCE-HY-146066A-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

(R)-alpha7 nAchR-JAK2-STAT3 agonist 1 is the R-enantiomer of alpha7 nAchR-JAK2-STAT3 agonist 1 (HY-146066). alpha7 nAchR-JAK2-STAT3 agonist 1 is a potent alpha7 nAchR-JAK2-STAT3 agonist, with an IC50 value of 0.32 µM for nitric oxide (NO). alpha7 nAchR-JAK2-STAT3 agonist 1 effectively suppresses the expression of iNOS, IL-1beta, and IL-6 in murine RAW264.7 macrophages. alpha7 nAchR-JAK2-STAT3 agonist 1 can inhibit LPS-induced NO release, NF-kappaB activation and cytokine production. alpha7 nAchR-JAK2-STAT3 can be used for researching sepsis[1].

Produkteigenschaften

• Molekulargewicht: 426.50
• Reinheit: 99.59
• Formel: C25H30O6
• Target-Kategorie: JAK,nAChR,NO Synthase,STAT

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound