MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 µM. MAO-B-IN-9 prevents Abeta1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Abeta1-42 anti-aggregation effects[1]. MAO-B-IN-9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molekulargewicht:
300.40
Reinheit:
99.70
CAS Nummer:
[2416910-88-6]
Formel:
C18H24N2O2
Target-Kategorie:
Amyloid-beta,Monoamine Oxidase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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