S-HP210 is a potent and selective glucocorticoid receptor (GR) with an IC50 value of 1.92 µM for NF-kappaB transrepression (TR). S-HP210 represses the LPS-induced transcription of a variety of proinflammatory genes such as IL-1beta, IL-6 and COX-2. S-HP210 is nontoxic at effective doses against mouse fibroblasts 3T3 cells[1].
Molekulargewicht:
421.54
Reinheit:
98.12
Formel:
C22H19N3O2S2
Target-Kategorie:
Glucocorticoid Receptor,NF-kappaB
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
