USP7-IN-9 is a highly potent ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 value of 40.8 nM. USP7-IN-9 can induce apoptosis and arrest cell progression at G0/G1 and S phases in RS4, 11 cells. USP7-IN-9 reduces the protein levels of oncoproteins MDM2 and DNMT1 and increases the protein levels of tumor suppressors p53 and p21[1].
Molekulargewicht:
779.08
Reinheit:
98.10
CAS Nummer:
[2444374-01-8]
Formel:
C32H33ClF6N6O8
Target-Kategorie:
Apoptosis,Deubiquitinase
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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