PY109 is an orally active and highly selective aryl hydrocarbon receptor (AHR) agonist. PY109s EC50 values in human-derived HepG2 and mouse Hepa-1c1c7 cells are 1.2 nM and 1.4 nM respectively. PY109 significantly upregulates the expression of CYP1A1 and IL-22, and inhibits the expression of IL-17A. PY109 significantly improves colitis in mice. PY109 can be used for research on colitis[1].
Molekulargewicht:
290.24
CAS Nummer:
[2378039-23-5]
Formel:
C15H9F3N2O
Target-Kategorie:
Aryl Hydrocarbon Receptor,Cytochrome P450,Interleukin Related
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
