MYF-03-69, CAS [[2416418-11-4]]

Produktübersicht

• Artikelname: MYF-03-69, CAS [[2416418-11-4]]
• Artikelnummer: MCE-HY-147135
• Hersteller Artikelnummer: HY-147135
• Alternativnummer: MCE-HY-147135-100MG,MCE-HY-147135-25MG,MCE-HY-147135-50MG,MCE-HY-147135-5MG,MCE-HY-147135-10MG,MCE-HY-147135-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: TEAD-IN-3

Produktbeschreibung

MYF-03-69 (TEAD-IN-3) is a covalent and irreversible TEAD inhibitor with IC50s of 385, 143, 558 and 173 nM for TEAD1, TEAD2, TEAD3 and TEAD4. MYF-03-69 disrupts YAP-TEAD association, suppresses TEAD transcriptional activity (IC50 = 56 nM) and up-regulates apoptosis gene BMF. MYF-03-69 selectively inhibits mesothelioma cancer cells with defective Hippo signaling. MYF-03-69 can be used for the study of malignant pleural mesothelioma (MPM)[1].

Produkteigenschaften

• Molekulargewicht: 443.42
• Reinheit: 98.11
• CAS Nummer: [2416418-11-4]
• Formel: C22H20F3N5O2
• Target-Kategorie: Apoptosis,YAP

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound