CCR4 antagonist 3 is a potent chemokine receptor 4 (CCR4) antagonist with an IC50 value of 1.7 µM for [125I]TARC (thymus and activation regulated chemokine). CCR4 antagonist 3 inhibits binding of radiolabeled TARC and macrophage-derived chemokine (MDC) to CCR4 receptors on the surface of CEM cells. CCR4 antagonist 3 also inhibits the in vitro migration of CEM cells mediated by TARC (IC50 = 6.4 µM)[1].
Molekulargewicht:
240.32
Reinheit:
99.94
CAS Nummer:
[1957-01-3]
Formel:
C14H12N2S
Target-Kategorie:
CCR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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