ARUK3001185 is a potent, selective, orally active and brain-penetrant inhibitor of Notum (IC50 = 6.7 nM). ARUK3001185 can restore Wnt signaling in the presence of Notum in vitro. ARUK3001185 is selective against serine hydrolases, kinases, and drug targets. ARUK3001185 can be used to research the role of Notum plays in diseases[1].
Molekulargewicht:
282.05
Reinheit:
99.28
CAS Nummer:
[2411969-39-4]
Formel:
C9H4Cl2F3N3
Target-Kategorie:
Wnt
Anwendungsbeschreibung:
MCE Product type: Reference compound
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