ALK-IN-22 (compound I-24) is a potent ALK inhibitor with IC50 values of 2.3, 3.7 and 2.9 nM for ALK, ALKL1196M and ALKG1202R, respectively. ALK-IN-22 down-regulated the phosphorylation of ALK and its downstream proteins. ALK-IN-22 induces apoptosis. ALK-IN-22 can be used for tumor research[1].
Molekulargewicht:
477.95
CAS Nummer:
[2468219-09-0]
Formel:
C24H24ClN7O2
Target-Kategorie:
Anaplastic lymphoma kinase (ALK),Apoptosis
Anwendungsbeschreibung:
MCE Product type: Reference compound
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