PROTAC EGFR degrader 7 (diTFA)

Produktübersicht

• Artikelname: PROTAC EGFR degrader 7 (diTFA)
• Artikelnummer: MCE-HY-147858A
• Hersteller Artikelnummer: HY-147858A
• Alternativnummer: MCE-HY-147858A-100MG,MCE-HY-147858A-10MG,MCE-HY-147858A-50MG,MCE-HY-147858A-5MG,MCE-HY-147858A-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC EGFR degrader 7 (compound 13b) is a potent and selective CRBN-recruiting PROTAC EGFRL858R/T790M degrader, with a DC50 of 13[1].2 nM.PROTAC EGFR degrader 7 inhibits NCI-H1975 cells proliferation, with an IC50 of 46[1].82 nM.PROTAC EGFR degrader 7 significantly induces apoptosis and G2/M phase arrest in NCI-H1975 cell.PROTAC EGFR degrader 7 shows antitumor activity, and can be used for non-small cell lung cancer (NSCLC) research[1].

Produkteigenschaften

• Molekulargewicht: 1064.98
• Reinheit: 99.19
• Formel: C50H50F6N10O10
• Target-Kategorie: PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound