EGFR-IN-62, CAS [[2890261-65-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-147862
Hersteller Artikelnummer:
HY-147862
Alternativnummer:
MCE-HY-147862-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
EGFR-IN-62 (compound 9h) is a potent and reversible EGFR kinase inhibitor, with IC50 values of 10 nM (L858R/T790 M), 29 nM (WT), and 242 nM (L858R/T790 M/C797S), respectively. EGFR-IN-62 shows antiproliferative activity against A549 and H1975 cell lines, with IC50 values of 2.53 and 1.56 µM, respectively. EGFR-IN-62 induces dose-dependent apoptosis process, G1/G0-phase arrestation, and the inhibition of motility on A549 and/or H1975 cell lines[1].
Molekulargewicht:
551.64
CAS Nummer:
[2890261-65-9]
Formel:
C30H33N9O2
Target-Kategorie:
Apoptosis,EGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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