Avacincaptad pegol, CAS [[1613641-69-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-148457
Hersteller Artikelnummer:
HY-148457
Alternativnummer:
MCE-HY-148457-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
Izervay
Avacincaptad pegol (Izervay) is a selective inhibitor targeting complement component C5, and is a pegylated ribonucleic acid aptamer. Avacincaptad pegol inhibits the cleavage of C5 into pro-inflammatory C5a and C5b, which forms the membrane attack complex (C5b-9), thereby reducing inflammatory cell recruitment and retinal cell damage. Avacincaptad pegol can slow the growth of geographic atrophy (GA) lesions and reduce the risk of persistent vision loss. Avacincaptad pegol can be used in research of geographic atrophy associated with age-related macular degeneration (AMD) and has been approved by the FDA[1][2].
Molekulargewicht:
52603 (Approximately)
CAS Nummer:
[1613641-69-2]
Target-Kategorie:
Complement System
Anwendungsbeschreibung:
MCE Product type: Oligonucleotides
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