Sograzepide (Netazepide, YF 476, YM-220) is an extremely potent, highly selective and orally active Gastrin/CCK-B antagonist with an IC50 value of 0.1 nM, has inhibitory effect on Gastrin/CCK-A activity with an IC50 of 502 nM[1]. Sograzepide (Netazepide, YF 476, YM-220) replaces the specific binding of [125I]CCK-8 to the rat brain, cloned canine and cloned human Gastrin/CCK-B receptors, with Ki values of 0.068, 0.62 and 0.19 nM, respectively[2].
Molekulargewicht:
498.58
Reinheit:
98.28
CAS Nummer:
[155488-25-8]
Formel:
C28H30N6O3
Target-Kategorie:
Cholecystokinin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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