Dipraglurant (ADX48621) is a potent, selective, orally active and brain penetrant mGluR5 negative allosteric modulator (NAM), with an IC50 of 21 nM. Dipraglurant can reduce Levodopa-induced dyskinesia (LID) in vivo[1][2]. Dipraglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molekulargewicht:
265.29
Reinheit:
99.97
CAS Nummer:
[872363-17-2]
Formel:
C16H12FN3
Target-Kategorie:
mGluR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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