18beta-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)) is a potent type 2 11beta-hydroxysteroid dehydrogenase (11beta-HSD2) inhibitor with an IC50 of 0.10 µM using rat kidney microsome. 18beta-Glycyrrhetyl-3-O-sulfate is the major metabolite of Glycyrrhetinic acid (GA). 18beta-Glycyrrhetyl-3-O-sulfate is the substrate of organic anion transporter (OAT) 1 and OAT3. 18beta-Glycyrrhetyl-3-O-sulfate has anti-inflammatory effects and has the potential for pseudohyperaldosteronism research[1][2].
Molekulargewicht:
550.75
Reinheit:
98.01
CAS Nummer:
[10251-38-4]
Formel:
C30H46O7S
Target-Kategorie:
11beta-HSD,Drug Metabolite,OAT
Anwendungsbeschreibung:
MCE Product type: Reference compound
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