Zavondemstat (sodium), CAS [[2908753-07-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-148807C
Hersteller Artikelnummer:
HY-148807C
Alternativnummer:
MCE-HY-148807C-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
QC8222 (sodium), TACH 101 (sodium)
Zavondemstat (QC8222, TACH 101) sodium is an orally active pan-KDM4 inhibitor, with a IC50 0.08 µM against human KDM4A-D and a K of 0.52 µM against human KDM4C. Zavondemstat sodium induces cell apoptosis, causes S-phase cell cycle arrest, reduces the population of tumor-initiating cells and inhibits cancer cell proliferation. Zavondemstat sodium suppresses tumor growth and induces tumor regression in mouse xenograft models. Zavondemstat sodium can be used for the research of various cancers including colorectal cancer, esophageal squamous cell carcinoma and triple-negative breast cancer[1].
Molekulargewicht:
453.51
CAS Nummer:
[2908753-07-9]
Formel:
C26H28N3NaO3
Target-Kategorie:
Apoptosis,Histone Demethylase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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