18:0,18:1 PS is the dominant phosphatidylserine subtype in cells, exosomes and HIV particles. It is abundant in the brain and is essential for maintaining membrane structure, lipid raft organization and intracellular trafficking. 18:0,18:1 PS mediates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids, and can induce the clustering of glycosylphosphatidylinositol-anchored proteins. In addition, clusters formed by the binding of 18:0,18:1 PS to cholesterol not only facilitate the proper distribution of cholesterol in lipid bilayers, but also effectively protect cholesterol from oxidative damage[1][2].
Molekulargewicht:
790.06
Reinheit:
99.95
CAS Nummer:
[124262-93-7]
Formel:
C42H80NO10P
Target-Kategorie:
Endogenous Metabolite,Liposome
Anwendungsbeschreibung:
MCE Product type: Natural Products
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