NXPZ-2, CAS [[2254492-08-3]]

Produktübersicht

• Artikelname: NXPZ-2, CAS [[2254492-08-3]]
• Artikelnummer: MCE-HY-149010
• Hersteller Artikelnummer: HY-149010
• Alternativnummer: MCE-HY-149010-10MMX1ML,MCE-HY-149010-25MG,MCE-HY-149010-1MG,MCE-HY-149010-50MG,MCE-HY-149010-10MG,MCE-HY-149010-100MG,MCE-HY-149010-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

NXPZ-2 is an orally active Keap1-Nrf2 protein-protein interaction (PPI) inhibitor with a Ki value of 95 nM, EC50 value of 120 and 170 nM. NXPZ-2 can dose-dependently ameliorate Abeta[1-42]-Induced cognitive dysfunction, improve brain tissue pathological changes in Alzheimers disease (AD) mouse by increasing neuron quantity and function. NXPZ-2 can inhibit oxidative stress by increasing Nrf2 expression levels and promoting its cytoplasm to nuclear translocation, which is helpful for Keap1-Nrf2 PPI inhibitors and AD associated disease research[1].

Produkteigenschaften

• Molekulargewicht: 597.66
• Reinheit: 98.18
• CAS Nummer: [2254492-08-3]
• Formel: C27H27N5O7S2
• Target-Kategorie: Keap1-Nrf2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound