Apricitabine, CAS [[160707-69-7]] Preis auf Anfrage
Artikelnummer:
MCE-HY-14913
Hersteller Artikelnummer:
HY-14913
Alternativnummer:
MCE-HY-14913-1MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
SPD754, AVX754
Apricitabine (SPD754, AVX754), the (-) enantiomer of 2'-deoxy-3'-oxa-4'-thiocytidine (dOTC), is a highly selective and orally active HIV-1 reverse transcriptase (RT) inhibitor (Ki=0.08 µM), as well as inhibits DNA polymerases alpha, beta, and gamma with Ki value of 300 µM, 12 µM, and 112.25 µM, respectively[1]. Apricitabine (SPD754, AVX754) shows promising antiretroviral efficacy, good tolerability and a low propensity for resistance selection in antiretroviral-naive HIV infection[2].
